Nuplura PH + 5 from Elanco provides cattle with strong protection against M. haemolytica, BVD (Types 1 and 2), IBR, BRSV, and PI3. Nuplura PH + 5 is the first refined BRD vaccine that doesn't contribute to endotoxin load, thereby minimizing the risk of adverse reactions like fever, sweats, and other setbacks. This means your calves experience smoother protection and can stay on feed, even during periods of elevated stress such as changes in weather, weaning, branding, shipping, and commingling. Nuplura PH + 5 uses recombinant technology and outer membrane proteins, a dual-action approach resulting in smooth, effective protection. It provides protective immunity in as few as 10 days and is gentle enough to be administered to calves as young as 28 days. Directions: Administer a 2 ml dose subcutaneously, followed by a second dose of monovalent BRSV vaccine 14 to 28 days after the first dose.