IBR, BVD Types I and II, PI3, BRSV and 5 strains of Lepto. Give 2 ml SQ. For primary vaccination, booster with BRSV in 2-4 weeks. Calves vaccinated before weaning should be revaccinated 30 days after weaning. Annual booster is recommended. Modified live, requires mixing. Safe for pregnant cows, or calves nursing pregnant cows, providing cows were vaccinated according to label directions with Titanium 5, Titanium L5 HB, Titanium 4L5,or Titanium 3, 30 to 60 days prior to breeding.